The results of the SLRC consortium are published in international journals to make relevant information available to the public.

1. Aina-Cathrine Øvergård, Christiane Eichner, Frank Nilsen, Sussie Dalvin
Molecular characterization and functional analysis of a salmon louse (Lepeophtheirus salmonis, Krøyer 1838) heme peroxidase with a potential role in extracellular matrixes.
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. Volume 206, April 2017, Pages 1–10

2. Helgesen KO, Bakke MJ, Kaur K, Horsberg TE. Increased catalase activity — A possible resistance mechanism in hydrogen peroxide resistant salmon lice (Lepeophtheirus salmonis).
Aquaculture 2017; 468: 135-140.

3. Anna Z Komisarczuk, Sindre Grotmol, Frank Nilsen
Ionotropic Receptors signal host recognition in the salmon louse (Lepeophtheirus salmonis, Copepoda)

4. Elena Myhre Jensen, Sigmund Sevatdal, Marit Jørgensen Bakke, Kiranpreet Kaur, Tor Einar Horsberg
A selection study on a laboratory-designed population of salmon lice (Lepeophtheirus salmonis) using organophosphate and pyrethroid pesticides. PLoS ONE 12(5): e0178068.

5A Borchel, AZ Komisarczuk, A Rebl, T Goldammer, F Nilsen
Systematic identification and characterization of stress-inducible heat shock proteins (HSPs) in the salmon louse (Lepeophtheirus salmonis)
Cell Stress and Chaperones, DOI 10.1007/s12192-017-0830-9, June 2017

6. LE Robin Ljungfelt, MQuintela, FBesnier, F Nilsen, KA Glover
A pedigree-based experiment reveals variation in salinity and thermal tolerance in the salmon louse, Lepeophtheirus salmonis
Wiley Evolutionary Applications

7. K Kaur, F Besnier, K Glover, F Nilsen, VT Aspehaug, H Børretzen Fjørtoft, TE Horsberg
The mechanism (Phe362Tyr mutation) behind resistance in Lepeophtheirus salmonis pre-dates organophosphate use in salmon farming.
Scientific Reports 2017; 7: 12349, September 2017

8. H Børretzen Fjørtoft, F Besnier, A Stene, F Nilsen, PA Bjørn, AK Tveten, B Finstad, VAspehaug,  KA Glover
The Phe362Tyr mutation conveying resistance to organophosphates occurs in high frequencies in salmon lice collected from wild salmon and trout.
Scientific Reports 2017 ;Volum 7:14258. s. 1-10, October 2017

9. K Glover, TJ Hansen, F Besnier, MF Solberg, PG Fjelldal, AG Eide Sørvik, S Dalvin,
F Nilsen
Cloned and outbred Atlantic salmon display equal parasite dispersion when infected with the salmon louse.
Aquaculture 2017 ;Volum 480. s. 83-88, November 2017

10. MT Khan, S Dalvin, F Nilsen, R Male
Microsomal triglyceride transfer protein in the ectoparasitic crustacean salmon louse (Lepeophtheirus salmonis).
Journal of Lipid Research 2017 ;Volum 58.(8) s. 1613-1623, August 2017

11.  AC Øvergård, LA Hamre, H Kongshaug, F Nilsen
RNAi-mediated treatment of two vertically transmitted rhabdovirus infecting the salmon louse (Lepeophtheirus salmonis).
Scientific Reports 2017 Oct 25;7(1):14030. doi: 10.1038/s41598-017-14282-3



1. Celia Agusti, Sandra Bravo, Gustavo Contreras, Marit J. Bakke, Kari O. Helgesen, Cristina Winkler, Ma. Teresa Silva, Julio Mendoza and Tor E. Horsberg.  Sensitivity assessment of Caligus rogercresseyi to anti-louse chemicals inrelation to treatment efficacy in Chilean salmonid farms.
Aquaculture, Volume 458, 1 May 2016, Pages 195–205

2. Aaen SM, Hamre LA and Horsberg TE. A screening of medicinal compounds for their effect on egg strings and nauplii of the salmon louse Lepeophtheirus salmonis (Krøyer).
Journal of Fish Diseases, 2016 Apr 1. doi: 10.1111/jfd.12462

3. Aaen SM and Horsberg TE. A screening of multiple classes of pharmaceutical compounds for effect on preadult salmon lice Lepeophtheirus salmonis. Journal of Fish Diseases, 2016 Apr 1. doi: 10.1111/jfd.12463

4. Kaur K, Jansen PA, Aspehaug VT and Horsberg TE. Phe362Tyr in AChE: A Major Factor Responsible for Azamethiphos Resistance in Lepeophtheirus salmonis in Norway.
PLoS ONE 2016, 11(2): e0149264. doi:10.1371/journal.pone.0149264

5. Jansen PA, Grøntvedt RN, Tarpai A, Helgesen KO, Horsberg TE. Surveillance of the Sensitivity towards Antiparasitic Bath-Treatments in the Salmon Louse (Lepeophtheirus salmonis).
PLoS ONE 2016, 11(2): e0149006. doi:10.1371/journal.pone.0149006

6. Holm HJ, Wadsworth S, Bjelland A-K, Krasnov A, Evensen Ø and Skugor S. Dietary phytochemicals modulate skin gene expression profiles and result in reduced lice counts after experimental infection in Atlantic salmon.
Parasites & Vectors 2016 9:271, DOI: 10.1186/s13071-016-1537-y

7. Liv Sandlund, Frank Nilsen, Rune Male, Sussie Dalvin. The ecdysone receptor (EcR) is a major regulator of tissue development and growth in the marine salmonid ectoparasite, Lepeophtheirus salmonis (Copepoda, Caligidae)
Molecular and Biochemical Parasitology, Volume 208, Issue 2, August 2016, Pages 65–73

8. Aina-Cathrine Øvergård, Lars A. Hamre, Ewa Harasimczuk, Sussie Dalvin, Frank Nilsen, Sindre Grotmol. Exocrine glands of Lepeophtheirus salmonis (Copepoda: Caligidae): Distribution, developmental appearance, and site of secretion
Journal of Morphology, 19 September 2016, Doi 10.1002/jmor.20611

9. Holm HJ, Skugor S, Bjelland AK, Radunovic S, Wadsworth S, Koppang EO, Evensen Ø. Contrasting expression of immune genes in scaled and scaleless skin of Atlantic salmon infected with young stages of Lepeophtheirus salmonis.
Dev Comp Immunol. 2016 Oct 21. doi: 10.1016/j.dci.2016.10.008

10.Skugor S, Holm H, Bjelland AK, Pino J, Evensen Ø, Krasnov A, Wadsworth S Nutrigenomic effects of glucosinolates on liver, muscle and distal kidney in parasite-free and salmon louse infected Atlantic salmon
Parasites and Vectors. 2016 Dec 12;9(1):639

11. O’Shea B, Wadsworth S, Pino Marambio J, Birkett MA, Pickett JA, Mordue Luntz AJ.
Disruption of host-seeking behaviour by the salmon louse, Lepeophtheirus salmonis, using botanically derived repellents.
J Fish Dis. 2016 Aug 6. doi: 10.1111/jfd.12526.



1. Krasnov A., Wesmajervi Breiland M., Hatlen B., Afanasyev S., Stanko Skugor. Sexual maturation and administration of 17β-estradiol and testosterone induce complex gene expression changes in skin and increase resistance of Atlantic salmon to ectoparasite salmon louse.
General and Comparative Endocrinology; Volume 212, 1 February 2015, Pages 34–43

2. Aaen SM, Helgesen KO, Bakke MJ, Kaur K, Horsberg TE.
Drug resistance in sea lice: a threat to salmonid aquaculture.
Trends in Parasitology. Volume 31, Issue 2, February 2015, Pages 72–81

3.  Bravo S, Silva MT, Agusti C, Sambra K, Horsberg TE. The effect of chemotherapeutic drugs used to control sea lice on the hatching viability of egg strings from Caligus rogercresseyi.
Aquaculture 06/2015; 443. DOI: 10.1016/j.aquaculture.2015.03.011

4. Eichner C, Harasimczuk E, Nilsen F, Grotmol S, Dalvin S.
Molecular characterization and functional analysis of LsChi2, a chitinase found in the salmon louse (Lepeophtheirus salmonis salmonis, Krøyer 1838)

5. Eichner C, Dalvin S, Skern-Mauritzen R, Malde K, Kongshaug H, Nilsen F. Characterization of a novel RXR receptor in the salmon louse (Lepeophtheirus salmonis, Copepoda) regulating growth and female reproduction
BMC Genomics. 2015 Feb 14;16:81. doi: 10.1186/s12864-015-1277-y

6. Helgesen KO, Aaen SM, Romstad H, Horsberg TE. First report of reduced sensitivity towards hydrogen peroxide found in the salmon louse Lepeophtheirus salmonis in Norway.
Aquaculture Reports, Volume 1, May 2015, Pages 37-42

7. Kaur K, Bakke MJ, Nilsen F, Horsberg TE. Identification and molecular characterization of two acetylcholinesterases from the salmon louse, Lepeophtheirus salmonis.
May 04, 2015 •DOI: 10.1371/journal.pone.0125362

8. Kaur K, Helgesen KO, Bakke MJ, Horsberg TE. Mechanism behind Resistance against the Organophosphate Azamethiphos in Salmon Lice (Lepeophtheirus salmonis).
PLoS ONE 10(4):e0124220. doi:10.1371/journal.pone.0124220

9. Tz Chun Guo, Amr Ahmed Abdelrahim Gamil, Melanie Koenig, Øystein Evenesen. Sequence Analysis and Identification of New Isoform of EP4 Receptors in Different Atlantic Salmon Tissues (Salmo salar L.) and Its Role in PGE2 Induced Immunomodulation In Vitro
April 2, 2015 DOI: 10.1371/journal.pone.0120483

10. Trösse C, Kongshaug H, Dondrup M, Nilsen F. Characterisation of iron regulatory protein 1A and 1B in the blood-feeding copepod Lepeophtheirus salmonis Experimental Parasitology, Volume 157, October 2015, Pages 1–11

11. Núñez-Acuña G., Vera-Bizama F., Boltaña S., Hawes C., Pino Marambio J., Wadsworth S., Gallardo-Escárate C. In-feed additives modulate ionotropic receptor genes from the sea louse Caligus rogercresseyi: A comparative analysis in two host salmonid species. Aquaculture. 451, 20 January 2016. Pages 99-105

12. Núñez-Acuña G., Goncalves A.T., Valenzuela-Munoz V., Pino Marambio J.,Wadsworth S., Gallardo-Escárate C.Transcriptome immunomodulation of in-feed additives in Atlantic salmon Salmo salar infested with sea lice Caligus rogercresseyi. Fish and Shellfish Immunology. November 2015;47(1):450-460. Epub 2015 Sep 10.

13. Vera-Bizama F., Valenzuela-Munoz V., Teresa Gonçalves A., Pino Marambio J., Hawes C., Wadsworth S., Gallardo-Escarate C.Transcription expression of immune-related genes from Caligus rogercresseyi evidences host-dependent patterns on Atlantic and coho salmon.
Fish & Shellfish Immunology 2015 Oct 19; 47(2):725-731. doi: 10.1016/j.fsi. 2015.10.022. [Epub ahead of print]

14. Eichner C, Øvergård AC, Nilsen F, Dalvin S.
Molecular characterization and knock-down of salmon louse (Lepeophtheirus salmonis) prostaglandin E synthase.
Exp Parasitology, Volume 159, 2015 Dec. Pages 79-93



1. Aaen, Stian M
, Aunsmo A, Horsberg TE.
Impact of hydrogen peroxide on hatching ability of egg strings from salmon lice (Lepeophtheirus salmonis) in a field treatment and in a laboratory study with ascending concentrations.
Aquaculture, Volumes 422-423, 20 February 2014, pages 167-171

2. Trösse C, Nilsen F, Dalvin S.
RNA interference mediated knockdown of the KDEL receptor and COPB2 inhibits digestion and reproduction in the parasitic copepod Lepeophtheirus salmonis
Comparative Biochemistry and Physiology, Part B: Biochemistry and Molecular Biology, Volume 170, April 2014, Pages 1-9.

3. Eichner C, Nilsen F, Grotmol S, Dalvin S.
A method for stable gene knock-down by RNA interference in larvae of the salmon louse (Lepeophtheirus salmonis)
Experimental Parasitology, Vol 140, 2014, Pages 44-51

4. Helgesen KO, Bravo S, Sevatdal S, Mendoza J, Horsberg TE.
Deltamethrin resistance in the sea louse Caligus rogercresseyi (Boxhall and Bravo) in Chile: bioassay results and usage data for antiparasitic agents with references to Norwegian conditions.
Journal of Fish Diseases 2014, doi: 10.111/jfd.12223

 5. Oelckers K., Vike S., Duesund H., Gonzalez J., Wadsworth S., Nylund A. (2014).
Caligus rogercresseyi as a potential vector for transmission of Infectious Salmon Anaemia (ISA) virus in Chile.
Aquaculture. 420. 126-132.

6. Skern-Mauritzen R, Torrissen O, Glover KA. Pacific and Atlantic Lepeophtheirus salmonis (Krøyer, 1838) are allopatric subspecies: Lepeophtheirus salmonis salmonis and L. salmonis oncorhynchi subspecies novo
BMC Genetics, 2014, doi:10.1186/1471-2156-15-32

7. Lina Eva Robin Ljungfeldt, Per Gunnar Espedal, Frank Nilsen, Mette Skern-Mauritzenand Kevin Alan Glover
A common-garden experiment to quantify evolutionary processes in copepods: the case of emamectin benzoate resistance in the parasitic sea louse Lepeophtheirus salmonis
BMC Evolutionary Biology, 2014, doi:10.1186/1471-2148-14-108

8. Christiane Eichner, Lars Are Hamre, Frank Nilsen
Instar growth and molt increments in Lepeophtheirus salmonis (Copepoda: Caligidae) chalimus larvae.
ScienceDirect, 2014, DOI: 10.1016/j.parint.2014.10.006

9. Gamil AA, Guo T, König M, Evensen O.
Distribution of EP4 receptor in different Atlantic salmon (Salmo salar l.) tissues.
Dev Comp Immunol. 2014; .pii: S0145-305X(14)00245-6. (48 (1):143-150, 2015).

10. Økland, AL, Nylund A, Øvergård A-C, Blindheim S, Watanabe K, Grotmol S, Arnesen C-E, Plarre H
Genomic Characterization and Phylogenetic Position of Two New Species in Rhabdoviridae Infecting the Parasitic Copepod, Salmon Louse (Lepeophtheirus salmonis).
Plos one, Nov17, 2014, DOI: 10.1371

11. Besnier, F, Kent, M, Skern-Mauritzen, R, Lien, S, Malde, K, Edvardsen, RB, Taylor, S, Ljungfeldt, LE, Nilsen, F & Glover, KA (2014). Human-induced evolution caught in action: SNP-array reveals rapid amphi-atlantic spread of pesticide resistance in the salmon ecotoparasite Lepeophtheirus salmonis. BMC Genomics 15: 937.

12. Helle Holm, Nina Santi, Sissel Kjøglum, Nebojsa Perisic, Stanko Skugor, Øystein Evensen
Difference in skin immune responses to infection with salmon louse (Lepeophtheirus salmonis) in Atlantic salmon (Salmo salar L.) of families selected for resistance and susceptibility. Fish & Shellfish Immunology

13. Liv Sandlund, Frank Nilsen, Rune Male, Sindre Grotmol, Heidi Kongshaug, Sussie Dalvin. Molecular characterisation of the salmon louse, Lepeophtheirus salmonis salmonis (Krøyer, 1837), ecdysone receptor with emphasis on functional studies of female reproduction. International Journal for Parasitology, Volume: 45   Issue: 2-3   Pages: 175-185   Published: Feb 2015

14. Skilbrei O, Espedal PG, Nilsen F, Garcia EP, Glover KA.
Emamectin benzoate and substance EX prophylactic evaluation against salmon louse infestation of sea-ranched Atlantic salmon smolts. Diseases of Aquatic Organisms; doi:10.3354/dao0283

15. Gustavo Núñez-Acuña G., Valenzuela-Muñoz V., Pino-Marambio J., Wadsworth S., Gallardo-Escárate C.
Insights into the olfactory system of the ectoparasite Caligus rogercresseyi: Molecular characterization and gene transcription analysis of novel ionotropic receptors. Experimental Parasitology 145 (2014) 99–109.


SLRC Pulication list 2011-2013

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